Mansion accommodation & holiday rentals in Panama
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Top-rated mansion accommodation & rentals in Panama
Guests agree: These mansions are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama mansion rentals
Luxury mansion rentals
Serviced apartment in Panama City
4.78 out of 5 average rating, 32 reviewsPenthouse deluxe, 360º views and glass pool
Home in Río Hato
4.95 out of 5 average rating, 75 reviewsSpectacular beachfront house in Buenaventura!
Villa in Playa Venao
4.98 out of 5 average rating, 61 reviewsCasa Aqua: Amazing beach front house - Playa Venao
Villa in Bejuco
4.96 out of 5 average rating, 78 reviewsBeach house in Punta Chame, Villa frente al mar
Rental unit in Maria Chiquita
4.95 out of 5 average rating, 21 reviewsPenthouse in Playa Escondida 4 bedrooms
Villa in Río Hato
4.91 out of 5 average rating, 22 reviewsSecluded Villa in Buenaventura Golf and Resort
Villa in Las Escobas del Venado
4.95 out of 5 average rating, 21 reviewsBreathtaking Ocean Villa. Casa de Vida
Home in Anton Valley
5 out of 5 average rating, 26 reviewsLovely and Cousy house at El Valle
Pet-friendly mansion rentals
Rental unit in San Carlos District
4.98 out of 5 average rating, 83 reviewsAmazing Oceanfront apartment in San Carlos
Home in Playa Bluff
5 out of 5 average rating, 18 reviewsJungle House 100m from the beach
Home in San Carlos
4.93 out of 5 average rating, 90 reviewsBeach House-Ocean View Rooftop Jacuzzi & Pool
Condo in San Carlos District
4.97 out of 5 average rating, 38 reviewsPunta Caelo Beach Front View
Villa in Portobelo
5 out of 5 average rating, 44 reviewsEntire Villa with pool in front of beach!
Home in Gamboa
4.86 out of 5 average rating, 88 reviewsBirdHouse@ Gamboa Panamá Canal
Villa in Costa Esmeralda
4.97 out of 5 average rating, 71 reviews#1 Villa with pool, jacuzzi, pool table, ping pong.
Villa in Bocas del Toro
5 out of 5 average rating, 56 reviewsCasa del Mar - eco aqua villa
Mansion rentals with a pool
Villa in Río Hato
4.95 out of 5 average rating, 41 reviewsLuxury 4BR Villa + Guesthouse & Pool @Buenaventura
Condo in Maria Chiquita
5 out of 5 average rating, 24 reviewsPlaya Escondida Lux Beachfront Haven:Oceanview Apt
Rental unit in Río Hato
5 out of 5 average rating, 19 reviews4 Bedroom Private Pool Paradise in Buenaventura
Rental unit in Maria Chiquita
4.95 out of 5 average rating, 65 reviewsSpacious 4Br Beachside Getaway at Playa Escondida
Villa in Punta Chame
4.92 out of 5 average rating, 13 reviewsFREE NIGHT Amazing Beachfront Villa - Palm House
Villa in Costa Esmeralda
5 out of 5 average rating, 16 reviewsSpectacular 600-meter oceanfront beach house
Home in Bastimentos
4.8 out of 5 average rating, 99 reviewsSpacious, Over the Water Home with Plunge Pool
Rental unit in El Chirú
4.94 out of 5 average rating, 85 reviewsBuenaventura Golf & Beach Resort Lux Apartment
Destinations to explore
- Rentals with an accessible height bed Panama
- Rentals with a fire pit Panama
- Rentals with a home theatre Panama
- Bed and breakfasts Panama
- Smoking-friendly rentals Panama
- Loft rentals Panama
- Rentals with a sauna Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Beach condo rentals Panama
- Pet-friendly rentals Panama
- Hotel rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Bungalow rentals Panama
- Private suite rentals Panama
- Chalet rentals Panama
- Rentals with a fireplace Panama
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- Rentals with a washing machine and dryer Panama
- Rentals with breakfast Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
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- Tiny house rentals Panama
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- Monthly Rentals Panama
- Rentals with pools Panama
- Boat rentals Panama
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- Rentals with lake access Panama
- Townhouse rentals Panama
- Boutique hotel rentals Panama
- Cottage rentals Panama
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- Rentals with a hot tub Panama
- Wheelchair accessible rentals Panama
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- Rentals with beach access Panama
- Island rentals Panama
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- Tree house rentals Panama
- Villa rentals Panama
- Nature eco lodge rentals Panama
- Holiday home rentals Panama
- Rentals with a patio Panama
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